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Genomics Applications Developer

Joseph Thompson

Hi, I'm Joe — I build solutions for labs adopting cutting-edge genomic testing technologies, bridging molecular biology and software from the bench to the pipeline.

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Experience

A running record of roles across clinical and translational genomics, most recent first.

  1. Current

    Field Application Scientist, Automation and Extraction

    Revvity · Saint Paul, MN (Hybrid)

    • Deliver field application and technical support for automated liquid handling (Janus, Sciclone) and NGS extraction solutions (Chemagen, NextFlex) across the Midwest territory.
    • Lead on-site trainings, product demonstrations, and troubleshooting to drive adoption and retention across the client base.
    • Develop application-specific protocols on automated liquid handling systems, translating customer procedures into optimized, validated workflows.
    • Provide advanced programming and integration support for third-party device integrations, and optimize liquid handling performance.
    • Partner with sales specialists on pre- and post-sales presentations across the full product line, serving as the technical bridge between customers and commercial teams.
    • Provide key technical consultation on current and future automated application directions across the life sciences portfolio.
  2. Apr 2023 – Oct 2023

    Product Development Scientist

    Geneoscopy · St. Louis, MO

    • Served as molecular biology lead on the design, optimization, and validation of IVD assays across Geneoscopy's product pipeline.
    • Applied regulatory frameworks such as Title 21, alongside CLSI and ISO standards, to the design and validation of clinical laboratory processes.
    • Used R and Python to script data compilation and analysis, improving the efficiency and reliability of assay evaluation.
    • Built a probit regression analysis tool that supported FDA PMA submissions by demonstrating assay performance and regulatory compliance.
  3. Jun 2021 – Jan 2023

    Senior Developer

    Mayo Clinic · Translational Research, Innovation and Test Development Office

    • Led experimental design and execution for an NGS-based assay supporting germline and somatic testing.
    • Provided technical judgment to optimize NGS assay performance and improve CLIA/CAP laboratory processes.
    • Supported sequencing troubleshooting with clinical and bioinformatics teams.
    • Designed, wrote, and troubleshot automation programs for high-throughput assays.
    • Contributed to project documentation including SOPs, regulatory submissions, plans, and reports.
    • Mentored junior staff and learners (fellows, residents) across NGS chemistries, assay development, and experimental planning.
    • Contributed to publications, conference abstracts, and internal grant proposals.
  4. Jan 2018 – Jun 2021

    Developer

    Mayo Clinic · Clinical Genome Sequencing Laboratory

    • Designed and conducted experiments, from routine to complex, to validate new assays, procedure changes, and instruments.
    • Analyzed and interpreted data, summarizing results in written and oral reports per quality system requirements.
    • Designed and troubleshot experiments.
    • Presented project updates internally and to collaborators and stakeholders.
    • Provided technical review, direction, and feedback to others.
    • Proposed novel ideas and initiatives.
  5. Jun 2015 – Jan 2018

    Clinical Technologist

    Mayo Clinic · Molecular Genetics Laboratory

    • Performed high-complexity laboratory testing on patient specimens across assays and platforms including DNA/RNA extraction, PCR, RT-qPCR, MLPA, and gel electrophoresis.
    • Analyzed and reviewed testing results, including NGS data.
    • Maintained compliance with company quality and safety policies and procedures.
    • Identified problems affecting test performance and took authorized corrective action.
    • Participated in the Proficiency Testing Program and internal inspections as assigned.

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